girl dressed in nurse costume with pastel rainbow wig

Harley Quinn has finally broken things off once and for all with the Joker and attempts to make it on her own as the criminal Queenpin of Gotham City.

Batman and Nightwing are forced to team with the Joker's sometimes-girlfriend Harley Quinn to stop a global threat brought about by Poison Ivy and Jason Woodrue, the Floronic Man.