In eighteenth-dynasty Egypt, Sinuhe, a poor orphan, becomes a brilliant physician and with his friend Horemheb is appointed to the service of the new Pharoah. Sinuhe's personal triumphs and tragedies are played against the larger canvas of the turbulent events of the 18th dynasty. As Sinuhe is drawn into court intrigues he learns the answers to the questions he has sought since his birth.

Guillermo del Toro, Rian Johnson and other film luminaries look back at LA's historic Egyptian Theatre as it returns to its former movie palace glory.