After moving to a new town with her stressed-out parents and relentlessly popular little sister, Daria uses her acerbic wit and keen powers of observation to contend with the mind-numbingly ridiculous world of Lawndale High.

When Daria disappears after their first date, Marek finds her in a psychiatric hospital. Everything might be part of a disturbing game played by powerful pharmaceutical companies, though the truth may be more frightening than either of them realize.