Set in the year 2024 in post-apocalyptic America, 18-year old Vic and his telepathic dog, Blood, are scavengers in the desolate wilderness ravaged by World War IV, where survivors must battle for food and shelter in the desert-like wasteland. Vic and Blood eke out a meager existence, foraging for food and fighting gangs of cutthroats.

11 year old Davy discovers that a chained gentle dog, Buck, is badly wounded around the neck because of the thick, tight collar he is made to constantly wear by his unfeeling owner. When Buck comes through the fence and becomes stuck, Davy removes the collar. Even though the boy tells him to stay in his owner's yard, the dog follows him home.