Jack Sadelstein, a successful advertising executive in Los Angeles with a beautiful wife and kids, dreads one event each year: the Thanksgiving visit of his twin sister Jill. Jill's neediness and passive-aggressiveness is maddening to Jack, turning his normally tranquil life upside down.

A horror retelling of the nursery rhyme Jack and Jill. A group of friends grieving a recent loss meet up with one another only to discover they are being hunted by Jack and Jill.