A navy destroyer is at sea avoiding a pandemic on land

Their mission is simple: Find a cure. Stop the virus. Save the world. When a global pandemic wipes out eighty percent of the planet's population, the crew of a lone naval destroyer must find a way to pull humanity from the brink of extinction.

Iain Armitage interviews Sting about his Broadway musical The Last Ship.

As an epidemic of a lethal airborne virus - that kills within days - rapidly grows, the worldwide medical community races to find a cure and control the panic that spreads faster than the virus itself.

A catastrophic train derailment sends the city spiraling into chaos. But the derailment is just the beginning. A biological gas attack sees crash survivors collapsing and dying within minutes. And the sickness is rapidly spreading.

Air and Naval forces team up to test weapons with a live fire attack on a modern day destroyer.

In February, 2020, a luxury cruise ship carrying 3,700 people arrives in Yokohama Port. One passenger, who disembarked in Hong Kong, was confirmed to have the new coronavirus. The coronavirus has since spread rapidly on the cruise ship. More than 100 passengers complain of symptoms. The DMAT (Disaster Medical Assistance Team) is called to the port to respond. DMAT is specialized in responding to natural disasters like earthquakes and floods. They do not have experience or training in dealing with new virus outbreaks. Hideharu Yuki, who is a leader in DMAT, and government official Nobutaka Tatematsu command the cruise ship situation at the headquarters. Doctor Yukiyoshi Sendo and members of DMAT, including Haruto Sanada, decided to board the ship to deal with the situation.

The crew of the new American strategic missile submarine "Archelon" is struck by an unknown virus. The command must decide on removing the submarine from combat duty and sending the crew to quarantine.