There is value in everyone’s death.

The chilling and relentless Jigsaw killer returns to terrorize the city once again. When a gruesome murder victim emerges with unmistakable traces of Jigsaw's sinister methods, Detective Eric Matthews is thrust into a high-stakes investigation. To his surprise, apprehending Jigsaw seems almost too easy, but what he doesn't realize is that being caught is merely another piece of Jigsaw's intricate puzzle.

Jigsaw has disappeared. Along with his new apprentice Amanda, the puppet-master behind the cruel, intricate games that have terrified a community and baffled police has once again eluded capture and vanished. While city detective scrambles to locate him, Doctor Lynn Denlon and Jeff Reinhart are unaware that they are about to become the latest pawns on his vicious chessboard.

Despite Jigsaw's death, and in order to save the lives of two of his colleagues, Lieutenant Rigg is forced to take part in a new game, which promises to test him to the limit.

Special Agent Strahm is dead, and Detective Hoffman has emerged as the unchallenged successor to Jigsaw's legacy. However, when the FBI draws closer to Hoffman, he is forced to set a game into motion, and Jigsaw's grand scheme is finally understood.

Following Jigsaw's grisly demise, Detective Mark Hoffman is commended as a hero, but Agent Strahm is suspicious, and delves into Hoffman's past. Meanwhile, another group of people are put through a series of gruesome tests.