Two men left in the world being chased by women

Traverse a post-apocalyptic world in which a cataclysmic event decimates every mammal with a Y chromosome but for one cisgender man and his pet monkey. Follow the survivors in this new world as they struggle with their efforts to restore what was lost and the opportunity to build something better.

Based on one of the most critically acclaimed comics of all time. A mysterious plague has wiped out all men on the planet, and women are left to pick up the pieces of society. The only surviving man is Yorick, an amateur escape artist who is the key to the continual survival of the human race. Special Agent 355 is tasked to protect his life at all costs. Luckily, she's really good at her job.