Supervillains Harley Quinn, Bloodsport, Peacemaker and a collection of nutty cons at Belle Reve prison join the super-secret, super-shady Task Force X as they are dropped off at the remote, enemy-infused island of Corto Maltese.

A group of professional commandos have to rescue a young female hostage from the drug cartel. Once in the jungle, they're being killed one by one by a fearful enemy.