Lady in yellow dress confronts guy in scream mask in alley

A terrified toy salesman is mysteriously attacked, and at the hospital, babbles and clutches the year's most popular Halloween costume, an eerie pumpkin mask. Suddenly, Doctor Daniel Challis finds himself thrust into a terrifying nightmare.

After failing to kill stubborn survivor Laurie and taking a bullet or six from former psychiatrist Dr. Sam Loomis, Michael Myers has followed Laurie to the Haddonfield Memorial Hospital, where she's been admitted for Myers' attempt on her life. The institution proves to be particularly suited to serial killers, however, as Myers cuts, stabs and slashes his way through hospital staff to reach his favorite victim.

Spending her first Halloween alone, a recently divorced writer searches for inspiration from trick-or-treaters who come to her door. The night becomes a nightmare when one surprise visitor makes this Halloween one she will never forget.

Fifteen years after murdering his sister on Halloween Night 1963, Michael Myers escapes from a mental hospital and returns to the small town of Haddonfield, Illinois to kill again.