At the opening party of a colossal—but poorly constructed—skyscraper, a massive fire breaks out, threatening to destroy the tower and everyone in it.

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Firemen brothers Brian and Stephen McCaffrey battle each other over past slights while trying to stop an arsonist with a diabolical agenda from torching Chicago.

Years after the original Backdraft, Sean, son of the late Steve "Bull" McCaffrey, is assigned to investigate a deadly fire only to realize it is something much more sinister.