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A DEA agent and an undercover Naval Intelligence officer who have been tasked with investigating one another find they have been set up by the mob -- the very organization the two men believe they have been stealing money from.

For Rachel and June, the only way out is D.O.A., Dead On Arrival. Money runners and assassins for a powerful drug lord, they know way too much to just wash their hands and walk away from all the violence, death and destruction. But when Rachel is brutally murdered in a drug deal gone bad, June calls it quits and takes to the open road for survival. Escape isn't that easy, and her life becomes a living hell as she is sadistically "persuaded" by the FBI into setting up her ex-boss. Forced back into the game, yet driven by a righteous code of honor and a killer's instinct, June finds herself at the dead end of a one-way street ... from which the only way out is with both guns blazing!