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Lincoln Rhyme was the department's top homicide detective and leading expert in criminal forensics until an injury left him paralyzed, depressed, and incapable of working. But when a gruesome murder in Manhattan leaves detectives baffled, they call on Rhyme to help solve the mystery. Amelia Donaghy, a rookie cop whose quick thinking preserved a gruesome murder scene, is enlisted by Rhyme to be his on-the-scene forensics expert. With Amelia reluctantly acting as Rhyme's able-bodied go-between, the pair piece together cryptic clues the killer leaves behind at the scene of the crime, hoping to catch the grisly serial killer.

Former NYPD detective and forensic genius Lincoln Rhyme was at the top of his game until a serious accident at the hands of a notorious serial killer forced him out of the field. When Amelia Sachs, an intuitive young officer who has a gift for profiling, finds herself hot on the killer's trail, Rhyme finds a partner for this new game of cat and mouse.

A policeman has breakfast with his wife and children, and then prepares for the day's work. While on his beat, he finds and helps a lost child. Later, several officers try to save a woman who has attempted to drown herself. And there are some even more hazardous situations yet to come.

A policewoman unwittingly puts her family in danger when she uncovers corruption in her department.